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恶性肿瘤患者血清sIL-2R水平测定及其意义
引用本文:江圣勇,杭鹤云,周俊裕.恶性肿瘤患者血清sIL-2R水平测定及其意义[J].现代实用医学,1997(5).
作者姓名:江圣勇  杭鹤云  周俊裕
作者单位:宁波市第二医院!315010(江圣勇),慈溪市范市卫生院(杭鹤云),海军412医院(周俊裕)
摘    要:应用双抗体夹心ELISA法检测了48例恶性实体瘤患者血清SIL-2R水平,发现荷瘤患者血清的SIL-2R均明显高于对照者,伴转移者的SIL-2R高于不伴转移者;根治性切除后,血清SIL-2R明显下降,而姑息性切除者则无明显变化;术后复发时已下降的SIL-2R再次升高。提示血清SIL-2R可作为恶性肿瘤患者病情估计、疗效评价和术后复发的监测指标。

关 键 词:恶性肿瘤  可溶性白细胞介素-2受体

The significance and change or sIL-2R in serum of patients with malignant tumor
Jiang Shengyong, Hang Heyung,Zhou Junyu..The significance and change or sIL-2R in serum of patients with malignant tumor[J].Modern Practical Medicine,1997(5).
Authors:Jiang Shengyong  Hang Heyung  Zhou Junyu
Abstract:The soluble interleukin-2 receptor (sIL-2R)level in serum of patients with malignant tumor were measured by double antibodies sandwich ELISA. The result showed sIL-2R in serum of tumor-bearing patients was evidently higher than normal controls, also sIL-2R in the patients with metastasis increased much significantly. sIL-2R in serum fell down obviously after radical operation, but not changed after palliative resection. However when postoperative recurrence oc curred, sIL-2R in serum would rise again. So it's one of the good ways to measure sIL-2R in serum of malignant tumor patients for estimating prognosis, evaluating efficacy and supervising recurrence.
Keywords:Malignant tumor  Soluble interleukin-2 receptor
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