Platelet Aggregation Inhibiting and Anticoagulant Effects of Oligoamines,XXVIII: Oligoamines with Fluorescent Properties. Part C: Fluorescent Oligoamines with Enhanced Hydrophilic Properties

Fifteen fluorescent oligoamines with one or two fluorescent groups and two or three basic N-functions were prepared and tested for antiplatelet activity (Born-test). Five compounds involving three different fluorophores, i.e. 2-fluorenyl, 1-pyrenyl, and 9-phenanthryl, show an IC₅₀ of 7–11 μmol/L. They are suitable to serve as probes in the field of oligoamine-biopolymere interactions.