Idiopathic Hypercalciuria and Bone Health |
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| Authors: | Laura E. Ryan Steven W. Ing |
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| Affiliation: | 1. Center for Women??s Health, Division of Endocrinology, Diabetes and Metabolism, The Ohio State University, 333 McCampbell Hall, 1581 Dodd Drive, Columbus, OH, 43210, USA
2. Division of Endocrinology, Diabetes and Metabolism, The Ohio State University, Columbus, OH, 43210, USA
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| Abstract: | Calcium is an important participant in many physiologic processes including coagulation, cell membrane transfer, hormone release, neuromuscular activation, and myocardial contraction. The body cooperates in a sophisticated web of hormonally mediated interactions to maintain stable extracellular calcium levels. Calcium is vital for skeletal mineralization, and perturbations in extracellular calcium may be corrected at the expense of bone strength and integrity. The aim of this review is to delineate our current understanding of idiopathic hypercalciuria in the context of bone health, specifically its definition, etiology, epidemiology, laboratory evaluation, and potential therapeutic management. |
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