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Effect of a new immunosuppressant, FTY720, on joint allografts.
Authors:H Watanabe  Y Hamada  T Toshima  K Nagasawa  Y Sakano
Affiliation:Department of Orthopaedic Surgery, Yamanashi Medical College, Nakakomagun, Yamanashi-Ken, Japan.
Abstract:The immunosuppressive effects of a new agent, FTY720, on joint allografts were studied histologically in a rat model. Favorable results without side effects were obtained at a dose of 3.0 mg/kg/day. The authors believe that this agent is one of the most useful immunosuppressants in the reported experimental model.
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