Effect of a new immunosuppressant, FTY720, on joint allografts. |
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Authors: | H Watanabe Y Hamada T Toshima K Nagasawa Y Sakano |
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Affiliation: | Department of Orthopaedic Surgery, Yamanashi Medical College, Nakakomagun, Yamanashi-Ken, Japan. |
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Abstract: | The immunosuppressive effects of a new agent, FTY720, on joint allografts were studied histologically in a rat model. Favorable results without side effects were obtained at a dose of 3.0 mg/kg/day. The authors believe that this agent is one of the most useful immunosuppressants in the reported experimental model. |
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