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An evaluation of the effects of susceptibility changes on the water chemical shift method of temperature measurement in human peripheral muscle
Authors:Ian R. Young  Joseph V. Hajnal  Idris G. Roberts  Junxiao X. Ling  Roger J. Hill-Cottingham  Angela Oatridge  Jason A. Wilson
Abstract:Divergencies between chemical shift measurements of temperature and directly measured values using optical sensors have been studied in vivo in human peripheral muscle with the assistance of a variety of experimental and theoretical techniques. These include the modeling of both thermal and susceptibility changes using two- and three-dimensional finite element methods, as well as the use of multi-wavelength near infrared observations. The conclusion of these studies is that a simple temperature calibration is not accessible, with results affected by the complex response of the tissue itself.
Keywords:temperature measurement  chemical shift  thermal modeling  susceptibility effects
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