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Preferential adsorption of high density lipoprotein from blood plasma onto biomaterial surfaces |
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| Authors: | W. Breemhaar E. Brinkman D.J. Ellens T. Beugeling A. Banties |
| Affiliation: | 1. Department of Chemical Technology, Biomaterials Section, Twente University of Technology, PO Box 217, Enschede, The Netherlands;1. Organon Teknika B. V., Stationsplein 1, Boxtel, The Netherlands |
| Abstract: | In the present study a two step enzyme immuno assay (EIA) was used for the investigation of the adsorption of proteins and lipoproteins from solutions and from blood plasma onto polymer surfaces. It was found that only a small adsorption of the major blood proteins occurred from plasma Evidence is presented that the reason for this adsorption behaviour is a preferential adsorption of high density lipoprotein (HDL). |
| Keywords: | Biomaterial high density lipoprotein adsorption protein |
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