Behçet syndrome: A great imitator |
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| Institution: | 1. Department of Dermatology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Turkey;2. Department of Dermatology, Faculty of Medicine, Ahi Evran University, Kırşehir, Turkey;1. Clinic for Dermatovenerology “Cutis,”, Dubrovnik, Croatia;2. Department of Mass Communication, University of Dubrovnik, Dubrovnik, Croatia;3. Department for the History of Medicine, Croatian Academy of Arts and Sciences, Zagreb, Croatia;1. Department of Sense Organs, Sapienza University of Rome, Viale del Policlinico 155, 00100 Rome, Italy;2. Department of Otolaryngology-Head and Neck Surgery, Humanitas Clinical and Research Center, via Manzoni 56, 20089 Rozzano, MI, Italy;3. Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Viale del Policlinico 155, 00100 Rome, Italy |
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| Abstract: | Behçet syndrome is considered to be a multisystemic vasculitis involving the skin, mucosa, eyes, joints, nervous system, cardiovascular system, and gastrointestinal system. The exact pathogenesis of the disease is unknown, but autoimmune factors are thought to play the main role. Vasculitis in Behçet syndrome can involve any kind and size of vessels, and this explains why the disease has the ability of multisystemic involvement. The commonest clinical presentation of Behçet syndrome is recurrent and painful mucocutaneous ulcerations known as aphthosis. The other clinical manifestations vary among patients and populations. The disease tends to be more severe in men. Ocular, vascular, and central nervous system involvements are the major causes of morbidity and mortality. Behçet syndrome is a mimicker of many diseases with its several faces and considered as one of the great imitators in dermatology. |
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