Usefulness of Ultrasound in Differentiating Xanthogranulomatous Cholecystitis from Gallbladder Carcinoma |
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| Institution: | 2. Department of General Surgery, Peking University Third Hospital, Haidian District, Beijing 100191, China;3. Department of Pathology, Peking University Third Hospital, Haidian District, Beijing 100191, China;2. Seoul National University College of Medicine, Seoul, South Korea;3. Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, South Korea;2. Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;3. Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;2. Department of Emergency Medicine, George Washington University Medical Center, Washington, DC, USA;3. Department of Medicine, George Washington University Medical Center, Washington, DC, USA;4. Seed Global Health–Massachusetts General Hospital, Boston, Massachusetts, USA;5. MGH Global Health, Massachusetts General Hospital, Boston, Massachusetts, USA |
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| Abstract: | Our study was aimed at finding the ultrasound (US) features of xanthogranulomatous cholecystitis (XGC) and evaluating the usefulness of US in differentiating XGC from gallbladder carcinoma (GBC). Through use of an electronic medical record system and the picture archiving and communication system, 31 cases of XGC and 52 cases of GBC with both sonograms and pathologic results were identified. Sonographic features of the abnormal gallbladder were evaluated. The smooth and intact interface between gallbladder lumen and mucosa was observed in most XGC cases (23/31, 74.2%) but in no GBC cases. XGC featured hyper-echoic foci, small hypo-echoic nodules and a layered appearance in the lesion, which were more frequently seen in the XGC group than in the GBC group. In conclusion, US may prove useful in the differential diagnosis of XGC and GBC, but more studies are required. |
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