|
|||||
|
|
Transfer of Carbapenem-Resistant Plasmid from Klebsiella pneumoniae ST258 to Escherichia coli in Patient |
|
| Authors: | Moran G. Goren Yehuda Carmeli Mitchell J. Schwaber Inna Chmelnitsky Vered Schechner Shiri Navon-Venezia |
| Affiliation: | Tel Aviv Sourasky Medical Center, Tel Aviv, Israel (M.G. Goren, Y. Carmeli, I. Chmelnitsky, V. Schechner, S. Navon-Venezia);National Center for Infection Control, Tel Aviv (Y. Carmeli, M.J. Schwaber, S. Navon-Venezia) |
| Abstract: | Klebsiella pneumoniae carbapenemase (KPC) 3–producing Escherichia coli was isolated from a carrier of KPC-3–producing K. pneumoniae. The KPC-3 plasmid was identical in isolates of both species. The patient''s gut flora contained a carbapenem-susceptible E. coli strain isogenic with the KPC-3–producing isolate, which suggests horizontal interspecies plasmid transfer. |
| Keywords: | Horizontal gene transfer carbapenem-resistant plasmid KPC bacteria plasmids Klebsiella pneumoniae Escherichia coli antibiotic resistance Israel dispatch |