神经节细胞胶质瘤的影像诊断

目的：探讨神经节细胞胶质瘤（ganglioglioma，GG）的影像学特点，提高对这一少见脑肿瘤的认识。方法：回顾性分析经病理证实的10例GG的影像学表现。10例中，1例仅行CT平扫，5例行MR平扫＋增强扫描（其中1例同时行MR灌注成像（peffusion weighted imaging，PWI），1例同时行PWI及MR波谱成像（MR spectroscopy，MRS）），3例同时行CT及MPd扫描（包括平扫、增强及1例PWI）。结果：10．例中，1例为脑内多发病变，9例单发病变中，5例位于颞叶，2例于小脑，2例于基底节区。所有病变未见明显占位征象，瘤周水肿无或轻微。CT平扫3例中2例呈低密度，1例因病变小且位于左颞叶边缘，CT检查未发现病变；CT增强扫描2例见病变实性部分明显强化；MRI平扫8例病变呈T1WI低信号为主、T2WI高信号为主；DWI表现多样；MRI增强扫描8例呈环形强化、团片状强化、弥漫强化或无明显强化；PWI检查3例未见局部脑血容量（rCBv）升高；MRS检查1例仅显示NAA轻度减低，未见异常代谢产物。结论：GG的临床和影像表现有一定特点，联合应用多种影像学检查方法有助于该病变的术前诊断。

Imaging diagnosis of ganglioglioma

Objective：To evaluate the imaging characteristics of ganglioglioma （GG）. Methods：10 patients with pathologically proved GG were retrospectively reviewed, including 1 patient with only pre-contrast cr scan, 5 patients with pre-and post-contrast MR scan, 1 patient also tmderwem PWI and MRS, 3 patients with multiple imaging modalities including CT and MR scans. Results： 1 patient had multiple lesions. 9 patients had single lesion, which included 2 lesions in the cerebellum, 5 lesions in the temporal lobe, and 2 lesions in the basal ganglia. No markedly mass effect was found in all cases. No peritumoral edema was found in 8 cases and mild edema in 2 cases. CT scan was negative in one patient because the lesion was small and located at the border of the left temporal lobe. Hypodensity was seen on pre-contrast CT scan. Homogeneous or heterogeneous T1WI hypointensity and T2WI hyperintensity were seen on pre-eontrast MR scan. Peripheral enhancement, clump enhancement, diffuse enhancement or no appreciable enhancement was seen on post-contrast CT or MR scan. Perfusion imaging demonstrated no definite increased relative cerebral blood volume （rCBV） in the region of the mass. Spectro- scopic imaging demonstrated normal spectra within the region of the mass. Condusion： The clinical manifestation and imaging findings of GG are somehow characteristic. It is helpful for preoperative diagnosis of GG to combine multiple imaging modalities.