双侧乳腺切除加假体植入一期乳房重建治疗青年早期乳腺癌患者

目的探讨保留皮肤和乳头乳晕复合体的双侧乳腺切除及假体植入一期乳房重建在青年早期乳腺癌治疗中的临床应用。方法回顾性分析2006年1月至2011年3月接受保留皮肤及乳头乳晕复合体双侧乳腺切除加假体植入一期乳房重建术的21例青年早期乳腺癌患者临床资料。结果21例患者手术成功，术后美容效果优良。随访12—72个月（中位随访期为34个月），无局部复发和远处转移。结论对青年早期乳腺癌患者，在切除患乳同时预防性切除对侧乳房，即行保留皮肤和乳头乳晕复合体的双侧乳腺切除加一期假体植入重建乳房，美容效果好，临床疗效满意。

Immediate breast reconstruction with prosthetic implants following bilateral nipple preserving subcutaneous mastectomy for young patients with early breast cancer

Objective To evaluate the application of immediate breast reconstruction (IBR) with silicon prosthetic implants following bilateral nipple preserving subcutaneous mastectomy in treatment of young patients with early breast cancer.Methods We retrospectively analyzed the clinical data of 21 patients with breast cancer who underwent IBR with prosthetic implants following bilateral nipple preserving subcutaneous mastectomy from January 2006 to March 2011.Results The operations were successful and excellent cosmetic results were obtained in all cases.No local recurrence or remote metastasis was found during the follow-up of 12-72 months (median 34 months).Conclusion For the young patients with breast cancer,the mastectomy on the affected side together with prophylactic excision of the contralateral side,i.e.IBR with prosthetic implants following bilateral nipple preserving subcutaneous mastectomy can obtain satisfactory cosmetic and clinical results.