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| 诊断试验评价的Meta分析方法 | |
| 引用本文： | 刘云霞,王洁贞,庞春坤,刘建平. 诊断试验评价的Meta分析方法[J]. 中华流行病学杂志, 2005, 26(4): 294-296 |
| 作者姓名： | 刘云霞 王洁贞 庞春坤 刘建平 |
| 作者单位： | 1. 250033,济南,山东大学医学院第二医院山东大学循证医学研究所 2. 山东省皮肤病性病防治研究所 3. International Health Research Group,Liverpool School of Tropical Medicine,UK |
| 摘 要： | 目的介绍诊断试验评价的Meta分析方法。方法以7篇B超诊断脂肪肝的研究为例，运用调整SROC法对其进行综合评价。结果用调整SROC法求得B超的灵敏度为0．89(95％CI：0．87～0．92)，特异度为0．94(95％CI：0．92～0．96)，Q值为0．90。结果表明，B超的诊断价值较高，可作为脂肪肝诊断的有效方法。结论运用诊断试验评价的Meta分析方法，可对诊断试验的诊断价值做出综合评价，增加研究结论的统计功效，提高结论的可靠性。 |
| 关 键 词： | Meta分析方法 诊断试验评价 SROC 诊断价值 B超诊断 有效方法 统计功效 脂肪肝 灵敏度 特异度 可靠性 CI |
| 收稿时间： | 2004-02-26 |
| 修稿时间： | 2004-02-26 |
The use of Meta-analysis in the evaluation on diagnostic tests |
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| LIU Yun-xi,WANG Jie-zhen,PANG Chun-kun and LIU Jian-ping. The use of Meta-analysis in the evaluation on diagnostic tests[J]. Chinese Journal of Epidemiology, 2005, 26(4): 294-296 | |
| Authors: | LIU Yun-xi WANG Jie-zhen PANG Chun-kun LIU Jian-ping |
| Affiliation: | Institute of Evidence Based Medicine, The Second Hospital, School of Medicine, Shandong University, Jinan 250033, China. |
| Abstract: | Objective To introduce Meta-analysis in evaluating diagnostic tests.Method Adjusted SROC method was used in assessing 7 diagnostic tests on fatty liver.Results The pooled sensitivity and specificity of type B ultrasonography were 0.89 [95% confidence interval(CI): 0.87- 0.92 ] and 0.94 (95%CI: 0.92- 0.96 ) respectively while the Q value was 0.90 by adjusted SROC method.The results indicated that the diagnostic value of type B ultrasonography were high,thus could be regarded as an effective method for fatty liver diagnosis.Conclusion Meta-analysis on evaluating diagnostic tests could be used to assess the diagnostic test to increase the power of conclusion,and to improveits its reliability. |
| Keywords: | Meta-analysis Adjusted SROC method Diagnostic tests |
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