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腹腔镜胃癌根治术后腹腔冲洗液CEA mRNA的变化和意义
引用本文:青廉,余佩武,王自强,罗华星,刘伟.腹腔镜胃癌根治术后腹腔冲洗液CEA mRNA的变化和意义[J].中华消化外科杂志,2006,5(2):102-104.
作者姓名:青廉  余佩武  王自强  罗华星  刘伟
作者单位:400038,重庆,第三军医大学西南医院普通外科
摘    要:目的探讨腹腔镜胃癌根治术对腹腔脱落癌细胞的影响。方法收集44例行腹腔镜胃癌根治术患者胃癌切除前后腹腔冲洗液,并以RT-PCR方法检测腹腔冲洗液CEA mRNA表达情况。结果腹腔镜胃癌根治术患者CEA mRNA表达胃癌未切除时阳性率为27.3%(12/44),切除后阳性率为36.4%(16/44),两组之间差异无统计学意义(P>0.05)。结论腹腔镜胃癌根治术不增加腹腔胃癌细胞的脱落。

关 键 词:胃癌  癌胚抗原  腹腔镜  根治性胃切除
文章编号:1671-4555(2006)02-0102-03
修稿时间:2006年1月19日

Changes of CEA mRNA in peritoneal lavage after laparoscopy-assisted radical gastrectomy and its clinical significance
Qing Lian,Yu Peiwu,Wang Ziqiang,Luo Huaxing,Liu Wei.Changes of CEA mRNA in peritoneal lavage after laparoscopy-assisted radical gastrectomy and its clinical significance[J].Chinese Journal of Digestive Surgery,2006,5(2):102-104.
Authors:Qing Lian  Yu Peiwu  Wang Ziqiang  Luo Huaxing  Liu Wei
Abstract:Objective To investigate the effect of laparoscopic-assisted radical gastrectomy on gastric cancer cells in peritoneal lavage fluid from patients' with gastric cancer.Methods Peritoneal lavage fluid from 44 patients with gastric cancer was collected before and after laparoscopic-assisted radical gastrectomy to detect carcinoembryonic antigen(CEA) mRNA expression using RT-PCR.Results The pre-,and postoperative CEA mRNA positive rate was 27.3%(12/44) and 36.4%(16/44),respectively,and there was no significant difference(P>0.05).Conclusions Laparoscopic-assisted radical gastrectomy doesn't increase the intraperitoneal free cancer cells.
Keywords:gastric cancer  CEA mRNA  laparoscopic  radical gastrectomy
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