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The diagnostic value of image guided percutaneous fine needle aspiration biopsy in equivocal mediastinal masses
Authors:Mine G. Güllüoğlu  Zeki Kılıçaslan  Alper Toker  Göksel Kalaycı  Dilek Yılmazbayhan
Affiliation:(1) Istanbul Faculty of Medicine, Department of Pathology, Division of Cytopathology, Istanbul University, Istanbul, Turkey;(2) Istanbul Faculty of Medicine, Department of Respiratory Medicine, Istanbul University, Istanbul, Turkey;(3) Istanbul Faculty of Medicine, Department of Thoracic Surgery, Istanbul University, Istanbul, Turkey;(4) Istanbul Týp Fakültesi, Gögüs Cerrahisi Anabilim Dalý, Istanbul Universitesi, Cerrahi Monoblok, 4. kat, Millet cad. Çapa, Topkapý, 34390 Istanbul, Turkey
Abstract:Background and aims The aim of this study was to assess the diagnostic value of image guided percutaneous fine needle aspiration (FNA) biopsy in equivocal mediastinal masses.Patients Sixty-six patients with an equivocal mediastinal mass who underwent FNA biopsy between 1993 and 2003 were eligible for final analysis. The cytological and definitive diagnosis of masses were grouped as primary 22 (33%)−30 (46%) and secondary (metastatic) neoplasms 18 (27%)−18 (27%) and nonneoplastic lesions 20 (30%)−18 (%27) respectively.Results The diagnostic accuracy (%95 C.I.) of FNA biopsy for primary mediastinal neoplasms, secondary neoplasms and nonneoplastic lesions were found to be 93.3 (83.8–98.2)%, 100 (95.1–100)%, 93.3 (83.8–98.2)%, respectively.Conclusion Image guided percutaneous FNA biopsy is a safe and highly accurate diagnostic method for equivocal mediastinal masses.
Keywords:Mediastinum  Fine needle aspiration  Mediastinal mass  Cytology
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