原发性肠套叠血浆生长抑素测定及其临床意义

探讨血浆生长抑制含量在小儿原发性肠套叠发病及病理发展中的变化和作有和放射免疫测定法，测定４１例原发性肠套叠患儿血浆生长抑素含量值，并与６０例正常儿和１２例肠梗阻儿进行比较。结果血浆生长抑素含量在生后３个月达到峰值，之后逐渐下降。

Plasma somatostatin levels in intussusception

Objective To study the levels of plasma somatostatin throughout the course of intussusception.Methods Post prandial plasma somatostatin concentrations were measured with radioimmunoassay in 41 patients with intussusception, 12 patients with intestinal obstruction and 60 normal controls. Patients with intussusception were subdivided into air reduction, anaesthetic and operative groups. Results In the normal control group, the plasma somatostatin level peaked at 3 months of age and declined thereafter. The plasma somatostatin was lowest in the air reduction group, higher in the anaesthetic group and highest in the operative group. The plasma somatostatin level of the former group was significantly lower than that of the controls whereas the levels of the latter two groups were higher than that of the controls. The highest level was recorded in patients with intestinal obstruction.Conclusions Plasma somatostatin is implicated in the process of intussusception and can be used as a marker of the process. Somatostatin analogue may be potentially useful in non operative management of intussusception.