| Abstract: | The inhibitory action of the neuraminidase ofVibrio cholerae in Rauscher mouse leukemia was studied. After treatment of the spleen cells of leukemic mice with neuraminidase in doses of 50 units/ml or more, the ability of these cells to induce leukemia when injected into BALB/c mice was inhibited significantly. Neraminidase in the above concentration, if given by repeated parenteral injection, had no therapeutic action in Rauscher leukemia.D. I. Ivanovskii Institute of Virology, Academy of Medical Sciences of the USSR. Scientific-Research Laboratory of Experimental Immunobiology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR N. N. Zhukov-Verezhnikov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 82, No. 11, pp. 1357–1359, November, 1976. |
