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阿维A联合NB-UVB治疗泛发性斑块状银屑病疗效观察
引用本文:晏文,黄洋,曹碧兰. 阿维A联合NB-UVB治疗泛发性斑块状银屑病疗效观察[J]. 中国皮肤性病学杂志, 2009, 23(8)
作者姓名:晏文  黄洋  曹碧兰
作者单位:遵义医学院第一附属医院皮肤科,贵州,遵义,563003
摘    要:目的探讨阿维A联合窄谱中波紫外线(NB-UVB)照射治疗泛发性斑块状银屑病的疗效。方法将入选的65例患者分为两组,治疗组35例,予口服阿维A胶囊,同时行NB-UVB全身照射;对照组30例,仅予NB-UVB全身照射。两组疗程均为10周。结果治疗组有效率为91.43%,对照组为66.67%,两组有效率比较,差异有统计学意义(P<0.5),两组复发率比较,差异无统计学意义(P>0.05)。结论阿维A联合NB-UVB照射治疗泛发性重度斑块状银屑病疗效好,不良反应少。

关 键 词:阿维A  窄谱中波紫外线  斑块状银屑病,寻常性

Observation of the Efficacy of Acitretin Combined with NB-UVB on Generalized Psoriasis Plaque
YAN Wen,HUANG Yang,CAO Bi-lan. Observation of the Efficacy of Acitretin Combined with NB-UVB on Generalized Psoriasis Plaque[J]. The Chinese Journal of Dermatovenereology, 2009, 23(8)
Authors:YAN Wen  HUANG Yang  CAO Bi-lan
Abstract:Objective To investigate the efficacy of acitretin combined with narrow-band ultravioletB(NB-UVB) in the treatment of patients with psoriasis plaque. Methods A total of 65 patients with psoriasis plaque was randomly divided into treatment group(35 cases) and control group(30 cases). Treatment group was treated with acitretin and NB-UVB,while control group was treated with NB-UVB only. The two groups were both treated for 10 weeks. Results The effective rate was 91.43% in treated group,and 66.67% in control group. There was significant difference between two groups (P<0.05). The recurrence rate of the two groups has no significant difference(P<0.05). Conclusion Radiation of acitretin combined with NB-UVB is safe and can improve the therapy efficacy significantly for patients with generalized psoriasis plaque.
Keywords:Acitretin   NB-UVB   Plague psoriosis   Vulgaris
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