| 自拟芪参通络汤对缺血性中风患者血管内皮功能的影响 |
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| 引用本文： | 高磊,李菲菲,陈龙霏,焦静,张宪忠.自拟芪参通络汤对缺血性中风患者血管内皮功能的影响[J].中国中医急症,2014(8):1438-1440. |
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| 作者姓名： | 高磊 李菲菲 陈龙霏 焦静 张宪忠 |
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| 作者单位： | 山东中医药大学附属日照市中医医院,山东日照276800 |
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| 基金项目： | 山东省中医药科技发展计划项目（2011-292） |
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| 摘 要： | 目的 观察自拟参芪通络汤对缺血性中风患者血管内皮功能的影响.方法 将162例气虚血瘀兼水湿停滞证缺血性中风患者随机分为治疗组79例和对照组78例,对照组采用西医常规治疗,治疗组在此基础上给予自拟参芪通络汤口服,两组疗程均为14d.结果 治疗组治疗后内皮细胞依赖性舒张功能（FMD）及血管性假血友病因子（vWF）、非对称性二甲基精氨酸（ADMA）、内皮细胞钙黏蛋白（VE-Ca）等水平改善较对照组更加明显（P＜0.05）.结论 自拟芪参通络汤治疗缺血性中风,能够有效保护患者的血管内皮功能.
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| 关 键 词： | 自拟参芪通络汤 血管内皮功能 内皮细胞依赖性舒张功 血管性假血友病因子 非对称性二甲基精氨酸 内皮细胞钙黏蛋白 |
Effect of Self-made Qishen Tongluo Decoction on Endothelial Function of Patients with Ischemic Stroke |
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| Institution: | GAO Lei,LI Feifei,CHENG Longfei,et al.( Shandong University of TCM Affiliated Rizhao Hospital of TCM, Shandong,Rizhao 276800, China) |
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| Abstract: | Objective： To stucly the effect of self-made Qishen Tongluo decoction on endothelial function of patients with ischemic stroke. Methods： 162 Qi deficiency and blood stasis and wet stagnation syndrome patients with ischemic stroke were randomly chosen and divided into two groups： treatment group and the control group （treatment group 79 cases,control group 78 cases）. The control group was given conventional western therapy. The treatment group on the basis of that was given Qishen Tongluo decoction for 14 d. Result： After treatment, FMD and blood VWF, ADMA,VE-Ca levels of treatment group improved significantly higher than those of control group （P〈 0.05 ,P〈 0.01 ）. Conclusions： Self-made Qishen Tongluo decoction can effectively protect endothelial function of patients with ischemic stroke. |
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| Keywords: | Self-made Qishen Tongluo Decoction Endothelial function Endothelial dependent diastolic function Von willbrand factor Asymmetry dimethyl arginine Mucins endothelial cell calcium |
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