Institution: | 1.Division of Hematology and Oncology, Department of Medicine,University of Florida College of Medicine,Gainesville,USA;2.Department of Surgery,University of Florida College of Medicine,Gainesville,USA |
Abstract: | IntroductionPancreatic cancer is often diagnosed at late stages, where disease is either locally advanced unresectable or metastatic. Despite advances, long-term survival is relatively non-existent.DiscussionThis review article discusses clinical factors commonly encountered in practice that should be incorporated into the decision-making process to optimize patient outcomes, including performance status, nutrition and cachexia, pain, psychological distress, medical comorbidities, advanced age, and treatment selection.ConclusionIdentification and optimization of these clinical factors could make a meaningful impact on the patient’s quality of life. |