Complementary DNA sequence of the HLA-B*3924 allele. |
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| Authors: | E Estefanía N Gómez-Lozano R de Pablo M E Moreno C Vilches |
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| Affiliation: | Servicio de Immunología, Hospital Universitario Puerta de Hierro, Madrid, Spain. |
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| Abstract: | We have isolated the complete coding region of HLA-B*39 from a Spanish Caucasoid, using a new PCR primer for its 5' untranslated region. The cDNA matched partial genomic sequences of B*3924, an allele whose distribution appears to be restricted to Mediterranean and Arabian Caucasoids. A single amino acid change exclusive to B*3924 (threonine-98) distinguishes it from B*3903. |
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