Incidence of urinary tract infection among patients with type 2 diabetes in the UK General Practice Research Database (GPRD) |
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| Authors: | Ishan Hirji Zhenchao Guo Susan W Andersson Niklas Hammar Andres Gomez-Caminero |
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| Institution: | 1. Section of Endocrinology, Tulane University Health Sciences Center, New Orleans, LA, USA;2. Department of Internal Medicine, University of Pisa School of Medicine, Pisa, Italy;3. Department of Obesity and Endocrinology, University of Liverpool, Clinical Sciences Centre, University Hospital Aintree, Liverpool, United Kingdom;4. Astellas Pharma Global Development, Leiderdorp, Netherlands;5. Astellas Pharma Global Development, Northbrook, IL, USA |
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| Abstract: | The objective of this observational study was to quantify the incidence of urinary tract infections (UTI) among diabetes patients and compare this risk to patients without diabetes. Type 2 diabetes patients and a matched sample of patients without diabetes were identified from GPRD. Patients were followed for 1-year from their study index date until the first record of a UTI or a censored event. The incidence of UTI was 46.9 per 1000 person-years (95% confidence interval (CI) 45.8–48.1) among diabetes patients and 29.9 (95% CI 28.9–30.8) for patients without diabetes. Compared to the non-diabetes patients, the risk of UTI was 1.53 (95% CI 1.46–1.59) for all diabetes patients; and 2.08 (95% CI 1.93–2.24) for patients with previously diagnosed diabetes. In general practice, across gender and age, the risk of developing a UTI is higher for patients with type 2 diabetes compared to patients without diabetes. |
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