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支气管哮喘患者血清IL-10与IgE水平变化的研究
引用本文:邓民斌,胡苏荣,韦国桢. 支气管哮喘患者血清IL-10与IgE水平变化的研究[J]. 标记免疫分析与临床, 2002, 9(4): 196-198. DOI: 10.3969/j.issn.1006-1703.2002.04.003
作者姓名:邓民斌  胡苏荣  韦国桢
作者单位:常州市第二人民医院核医学科,江苏,常州,213003;常州市第二人民医院呼吸内科,江苏,常州,213003
摘    要:分别用ELISA、IRMA法对50例支气管哮喘急性发作患者和48名对照者血清IL-10、IgE进行测定.结果是: 支气管哮喘患者IL-10含量明显低于对照组(P<0.01), 而IgE含量则明显高于对照组(P<0.01), 两者之间呈明显负相关(r=-0.18,P<0.01).结论是: 支气管哮喘患者IL-10不足、IgE水平增高可能成为其发病的重要原因之一.

关 键 词:白细胞介素-10  免疫球蛋白-E
文章编号:1006-1703(2002)04-0196-03
修稿时间:2002-01-04

Study of IL-10 and IgE Levels in the Serum of Patients with Asthma
DENG Min-bin ,HU Su-rong ,WEI Guo-zhen. Study of IL-10 and IgE Levels in the Serum of Patients with Asthma[J]. Labeled Immunoassays and Clinical Medicine, 2002, 9(4): 196-198. DOI: 10.3969/j.issn.1006-1703.2002.04.003
Authors:DENG Min-bin   HU Su-rong   WEI Guo-zhen
Affiliation:DENG Min-bin 1,HU Su-rong 2,WEI Guo-zhen 2
Abstract:Using ELISA and IRMA respectively detected IL-10 and IgE levels in the serum of 50 patients with acute asthma and 48 healthy persons. Results show IL-10 levels in the serum of patients with asthma is obviously lower than that of healthy persons( P <0.01), but IgE levels in them are obviously higher than that of healthy persons ( P <0.01), there is negative correlation between IL-10 and IgE( r =-0.18, P < 0.01). Suggesting that Il-10 is insufficient and IgE is high in patients with asthma may be one of important causes of asthma.
Keywords:Interleukin-10  Immunoglobulin-E
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