| 支气管哮喘患者血清IL-10与IgE水平变化的研究 |
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| 引用本文： | 邓民斌,胡苏荣,韦国桢.支气管哮喘患者血清IL-10与IgE水平变化的研究[J].标记免疫分析与临床,2002,9(4):196-198. |
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| 作者姓名： | 邓民斌 胡苏荣 韦国桢 |
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| 作者单位： | 1. 常州市第二人民医院核医学科,江苏,常州,213003;2. 常州市第二人民医院呼吸内科,江苏,常州,213003 |
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| 摘 要： | 分别用ELISA、IRMA法对50例支气管哮喘急性发作患者和48名对照者血清IL-10、IgE进行测定.结果是: 支气管哮喘患者IL-10含量明显低于对照组(P＜0.01), 而IgE含量则明显高于对照组(P＜0.01), 两者之间呈明显负相关(r=-0.18,P＜0.01).结论是: 支气管哮喘患者IL-10不足、IgE水平增高可能成为其发病的重要原因之一.
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| 关 键 词： | 白细胞介素-10 免疫球蛋白-E |
| 文章编号： | 1006-1703(2002)04-0196-03 |
| 修稿时间： | 2002年1月4日 |
Study of IL-10 and IgE Levels in the Serum of Patients with Asthma |
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| DENG Min-bin ,HU Su-rong ,WEI Guo-zhen.Study of IL-10 and IgE Levels in the Serum of Patients with Asthma[J].Labeled Immunoassays and Clinical Medicine,2002,9(4):196-198. |
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| Authors: | DENG Min-bin HU Su-rong WEI Guo-zhen |
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| Institution: | DENG Min-bin 1,HU Su-rong 2,WEI Guo-zhen 2 |
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| Abstract: | Using ELISA and IRMA respectively detected IL-10 and IgE levels in the serum of 50 patients with acute asthma and 48 healthy persons. Results show IL-10 levels in the serum of patients with asthma is obviously lower than that of healthy persons( P <0.01), but IgE levels in them are obviously higher than that of healthy persons ( P <0.01), there is negative correlation between IL-10 and IgE( r =-0.18, P < 0.01). Suggesting that Il-10 is insufficient and IgE is high in patients with asthma may be one of important causes of asthma. |
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| Keywords: | Interleukin-10 Immunoglobulin-E |
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