| LC/MS分析加替沙星的光降解产物 |
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| 引用本文： | 陈海燕,李宁,林星渝. LC/MS分析加替沙星的光降解产物[J]. 华西药学杂志, 2004, 19(4): 304-305 |
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| 作者姓名： | 陈海燕 李宁 林星渝 |
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| 作者单位： | 1. 重庆医疗器械质量检验中心,重庆,400015
2. 重庆市药品检验所,重庆,400015 |
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| 摘 要： | 目的分析加替沙星的光降解产物。方法用液相色谱仪和液质联用仪进行分离和分析。结果确证加替沙星在光照后有降解产物产生。结论加替沙星应尽量避光使用，以保证产品的质量。
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| 关 键 词： | LC MS 加替沙星 降解产物 光降解物 |
| 文章编号： | 1006-0103(2004)04-0304-02 |
| 修稿时间： | 2004-03-01 |
Study on the structure of Gatifloxacin photodegradation products by HPLC and MS |
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| CHEN Hai-yan ,LI Ning ,LIN Xing-yu. Study on the structure of Gatifloxacin photodegradation products by HPLC and MS[J]. West China Journal of Pharmaceutical Sciences, 2004, 19(4): 304-305 |
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| Authors: | CHEN Hai-yan LI Ning LIN Xing-yu |
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| Affiliation: | CHEN Hai-yan 1,LI Ning 2,LIN Xing-yu 1 |
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| Abstract: | OBJECTIVE To study the structure of Gatifloxacin photodegradation products.METHODS The LC/MS method was developed for the separation and analysis of Gatifloxacin photodegradation products.RESULTS Photodegradation products were confirmed by LC/MS.CONCLUSION Gatifloxacin showed be stored away from light. |
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| Keywords: | Gatifloxacin Photodegradation products Structure LC/MS |
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