Phenolic constituents of the roots of Sophora flavescens |
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| Authors: | Shen Chien-Chang Lin Ting-Wei Huang Yu-Ling Wan Shr-Ting Shien Bor-Jinn Chen Chien-Chih |
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| Institution: | National Research Institute of Chinese Medicine, No. 155-1, Sec. 2, Li Nung Street, Peitou, Taipei, Taiwan, Republic of China. |
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| Abstract: | From the roots of Sophora flavescens collected in Taiwan, four new prenylflavonoids, sophoraflavanone K (1), sophoraflavanone L (2), 8-lavandulylkaempferol (3), and cyclokuraridin (4), a new arylbenzofuran, 2-(2,4-dihydroxy-5-prenylphenyl)-5,6-methylenedioxybenzofuran (5), and a new prenyldibenzoyl derivative, sophoradione (6), were isolated. The structures of 1-6 were determined by spectroscopic data analysis. Compounds 2-6 were evaluated for cytotoxic activity against the KB epidermoid carcinoma cell line. |
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