Adrafinil-induced orofacial dyskinesia. |
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| Authors: | Stéphane Thobois Jing Xie Helena Mollion Isabelle Benatru Emmanuel Broussolle |
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| Institution: | Department of Neurology, The Pierre Wertheimer Neurological Hospital, Lyon, France. stephane.thobois@chu-lyon.fr |
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| Abstract: | We describe the first case of orofacial abnormal movements induced by adrafinil, a vigilance promoting agent of the same pharmacological class as modafinil. The dyskinesias did not spontaneously recover despite adrafinil withdrawal for a 4-month period. They were secondly dramatically improved by tetrabenazine, a presynaptic dopaminergic depleting drug which was introduced after the 4-month adrafinil-free period. |
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| Keywords: | orofacial dyskinesias adrafinil tetrabenazine |
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