肝癌肝移植复发的干预

肝细胞肝癌传统的根治方法是手术切除,应用范围窄,肝移植术为肝癌患者提供了一个理想的根治性治疗方法,但肿瘤的复发和转移往往造成手术失败,因此对于手术而言,把握合理的手术指征是治疗成功的关键,新的化疗药物的发展,以及分子靶向药物的出现和在临床的广泛应用,进一步提升了围手术期全身化疗的作用,结合免疫抑制剂的合理调整,为肝癌根治治疗提供了希望。

Interference for recurrence of hepatocellular carcinoma after liver transplantation

Hepatic resection is considered curative treatment for patients with hepatocellular carcinoma (HCC),but the range of indication is narrow. Liver transplantation(LT) is another option, but recurrence and metastasis reduce long-term and medium-term survival. Appropriate patient selection is crucial in ensuring acceptable outcomes. Novel anticancer agents (chemotherapy and molecular target therapy) and appropriate use of immunosuppressant hold promise for improving the outcomes.