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Biopsy‐proven adenoviral diarrhea responding to low‐dose cidofovir
Authors:NP Nicolasora  P Reddy  DR Kaul
Institution:1. Department of Medicine, Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor, Michigan, USA;2. Blood and Bone Marrow Transplant Program, Department of Internal Medicine, Division of Hematology‐Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA
Abstract:Abstract: We present a case of diarrhea secondary to biopsy‐proven adenovirus (ADV) infection after autologous peripheral hematopoietic stem cell transplant for multiple myeloma. The patient had a negative plasma polymerase chain reaction for ADV and a dramatic clinical response to low‐dose cidofovir. To our knowledge, this is the first report in an adult hematopoietic stem cell recipient of the use of low‐dose cidofovir to treat proven ADV gastrointestinal infection.
Keywords:adenovirus  diarrhea  stem cell transplant  low‐dose cidofovir
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