恶性肉芽肿与中线淋巴瘤的临床观察

目的探讨恶性肉芽肿与中线淋巴瘤两种疾病的关系。方法自１９８９年１２月至１９９５年３月共收治恶性肉芽肿及中线淋巴瘤各２３例。两者在发病年龄、部位及首发症状相似。前者有７３．９％单用放射治疗，后者有６９．５％用放射治疗和化疗联合。病理类型前者为炎性坏死性肉芽组织，后者均为非霍奇金淋巴瘤（Ｔ细胞性１３例，Ｂ细胞性１例，未分型９例）。结果完全缓解率分别为８２．６％和６５．２％，２年生存率分别为８２．６％和７３．９％。结论两者不应视为同一疾病。

Clinical radiotherapeutic differentiation of malignant granuloma and midline lymphoma

Objective To differentiate malignant granuloma (MG) from midline lymphoma (ML) by radiotherapy.Methods From Dec. 1989 to Mar. 1995,23 cases of malignant granuloma and 23 cases of midline lymphoma were treated. These two kinds of disease were similar in the course, site and presenting symptoms. 73.9% patients with malignant granuloma were treated by radiotherapy alone, and 69.5% midline lymphoma patients were treated by combined radiotherapy and chemotherapy. Pathologically,the former was inflammatory necrotic granuloma and the latter was non Hodgkin's lymphoma (13 cases T cell,1 case B cell, and 9 cases unclassifiable).Results The complete response rates of MG and ML were 82.6 % and 65.2% respectively. Their 2 year survival rates were 82.6 % and 73.9% respectively.Conclusions Malignant granuloma and midline non Hodgkin's lymphoma should not be taken as one disease entity.