肛门癌61例治疗结果分析

目的分析肛门癌的治疗结果。方法１９５８年８月至１９８８年１２月，中国医学科学院肿瘤医院收治肛门癌６１例，４３例接受了单纯放射治疗；放射治疗＋手术治疗８例，根治术１０例。应用Ｋａｐｌａｎ－Ｍｅｉｅｒ方法分析疗后生存率。结果本组病例总的５年生存率为４４．３％，不同期别的５年生存率分别为：Ｔ１Ｎ０８１．８％，Ｔ２Ｎ０６８．５％，Ｔ３～４Ｎ０２５．０％，Ｔ２～４Ｎ１～２Ｍ０１０．０％，Ｔ２～４Ｎ０～１Ｍ１０．０％。肿瘤的分期是影响预后的重要因素。２３例单纯放射治疗的Ｔ１～２Ｎ０的病例５年生存率为７８．３％，５年无复发生存率为６６．８％，６１．０％（１４／２３）的病例保留了肛门功能。６例局部复发的病例中３例经补救治疗后获控制。结论早期肛门癌Ｔ１～２Ｎ０放射治疗可以达到与根治术相同的治愈率，并能够使大约２／３的患者保存肛门功能。放射治疗复发病例可以行手术补救治疗。对Ｔ２以上的病例应进行有计划的综合治疗研究。

Treatment of 61 patients with cancer of the anus

Objective To evaluate our treatment results of anal cancer. Methods Between 19581988, 61 patients with anal cancer were treated in our hospital, 43 received radiotherapy alone, 8 received radiotherapy plus surgery and 10 received abdomino-perineal resection. Kaplan-Meier method was used in the survival analysis. Results The overall 5year survival rate was 44.3%. For the different T stages, the 5year survival rates were: T1N0 81.8%, T2N0 68.5%, T34N0 25.0%, T24N1M0 10.0% and T24N01M0 0. 0%. TNM stage was most prognostic. For the 23 T12N0 cases treated with radiotherapy alone, the 5year survival rate was 78.3% with anal function preserved in 14 cases (61.0%).THZ Conclusions Radiotherapy alone for anal cancer has a high probability of survival in early cases with about twothirds of cases having their anal function preserved.