马鞍山地区606例流感样病例病毒分离和监测分析

目的阐明2005年10月至2006年4月马鞍山地区流行性感冒(流感)流行特点和流感病毒优势株的特性。方法流感病毒分离采用细胞分离;流感病毒亚型鉴定采用血球凝集抑制试验。结果2005年10月至2006年4月,全市3家国家流感监测哨点医院共采集流感样患者咽拭子标本共计606份,经鉴定流感病毒阳性69株,分离率11.4%。在69株流感病毒中,A1型14株、B型流感病毒Victoria55株,分别占总分离数的20.3%和79.7%,未分离到A3型和B型流感病毒Yamagada。优势流行株为H1N1和B型Victoria株。A1型流感病毒主要分离于2006年1月和2月,而B型Victoria系流感病毒主要集中分离于2￣4月。结论马鞍山地区感染人群的流感毒株依然以A型(H1N1)和B型Victoria为优势株。与全国监测相比,B型Victoria分离比例高。

Isolation of virus and analysis of surveillance among influenza-like cases in Maanshan Region

Objective The present study was conducted to clarify the epidemiological characteristics of influenza and the traits of dominant strains of influenza viruses in Maanshan Region from October 2005 to April 2006. Methods Influenza viruses were isolated by MDCK cell, and the subtypes were identified by hemagglutination inhibition test. Results During the period of October 2005 to April 2006, a total of 606 throat swabs of influenza-like patients were collected from 3 national influenza-monitoring hospitals in the whole city, and the influenza viruses were positive in 69 strains with the isolation rate of 11.4%. Of the 69 strains, 14 strains were influenza A1, and 55 strains were B/Victoria viruses with the isolation rates of 20.3% and 79.7% respectively. Influenza virus A3 and B/Yamagada were not found. The dominant strains were H1N1 and B/Victoria. Influenza A1 viruses were mainly isolated in January and February 2006, while B/Victoria viruses were isolated from February to April. Conclusion Among the infection population in Maanshan Region, the dominant strains of influenza viruses were A (H1N1) and B/Victoria type. Compared with the whole country, Influenza B/Victoria virus in Maanshan Region accounted for a higher proportion of the isolated viruses.