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克肝胶囊对大鼠慢性肝损伤的影响
引用本文:徐玉芳,黄向春,温子龙,罗佐阳,黄常青,雷元金.克肝胶囊对大鼠慢性肝损伤的影响[J].湖北中医学院学报,2001,3(1):15-16.
作者姓名:徐玉芳  黄向春  温子龙  罗佐阳  黄常青  雷元金
作者单位:广东省深圳市西乡人民医院,518102
基金项目:广东省中医药管理局资助项目! (NO :972 90 )
摘    要:用CCl4制成慢性肝损伤模型,克肝胶囊为治疗用药,观察肝功能、肝脏指数及肝组织病理等变化,以乙肝解毒胶囊作对照。结果:与乙肝解毒胶囊一样,克肝胶囊各剂量组都能显降低ALT、AST、肝脏指数、唾液酸和胶原蛋白含量(P<0.05或0.01);提高ALB、A/G(P<0.01)及改善肝脏病理。结论:克肝胶囊有抗慢性肝损伤作用。

关 键 词:慢性肝损伤  大鼠  克肝胶囊  实验研究
文章编号:1008-987X(2001)01-0015-02
修稿时间:2000年11月8日

Influence of Kegan Capsule on Chronic Hepatic Damage in Rats
Xu Yufang,Huang Xiangchun,Wen Zilong,et al..Influence of Kegan Capsule on Chronic Hepatic Damage in Rats[J].Journal of Hubei College of Traditional Chinese Medicine,2001,3(1):15-16.
Authors:Xu Yufang  Huang Xiangchun  Wen Zilong  
Institution:Xu Yufang,Huang Xiangchun,Wen Zilong,et al. Xixiang People's Hospital of Shenzhen City.Shenzhen 518102
Abstract:To observe the effect of Kegan capsule on chronic hepatic damage in rats.Methods:The rat models of chronic hepatic damage were made with CCl 4,after being treated by Kegan capsule,the changes of liver function,liver index and liver pathological tissue were observed,and compared with Yigan Jiedu capsule.Results:Each dosage group of Kegan capsule all could decrease the serum level of ALT,AST,liver index,saliva acid,the contents of collagen protein(P<005 or P<001),increase the level of Alb,A/G(P<001)and improve liver pathological tissue condition significantly as Yigan Jiedu capsule did.Conclusion:Kegan capsule have the function of resisting chronic hepatic damage.
Keywords:Chronic hepatic damage  Rat  Kegan capsule  Experimental study
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