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三维正脊疗法对豚鼠气道炎性细胞和气道重塑的影响
引用本文:刘军,项良碧,陈语,韩文峰,曹燕,李军.三维正脊疗法对豚鼠气道炎性细胞和气道重塑的影响[J].中国医药导刊,2008,10(6):904-905.
作者姓名:刘军  项良碧  陈语  韩文峰  曹燕  李军
作者单位:沈阳军区总医院骨科,沈阳,110015
摘    要:目的:探讨三维正脊疗法对豚鼠炎性细胞和气道重塑的影响。方法:选取3月龄豚鼠30只,雌雄不拘,按体重随机分为哮喘正脊组(10例)、哮喘组(10例)、空白对照组(10例)。予1%卵蛋白雾化吸入诱发哮喘建立支气管哮喘模型,正脊组同时行三维正脊疗法。2周后处死动物,取肺组织行HE染色,光镜下观察并进行图像分析。结果:空白对照组及哮喘正脊组炎性细胞及气道重塑均不明显。而哮喘组则可见大量炎性细胞及气道壁增厚、平滑肌增生明显。结论:三维正脊疗法可减少气道黏膜中炎性细胞的浸润,抑制气道重塑。

关 键 词:支气管哮喘  气道重塑  三维正脊疗法

Effects of Three-dimensional Rectification Apparatus on the Inflammatory Cells and Airway Remodeling of Guinea Pigs
Liu Jun Xiang Liang-bi Cheng Yu,et al..Effects of Three-dimensional Rectification Apparatus on the Inflammatory Cells and Airway Remodeling of Guinea Pigs[J].Chinese Journal of Medicinal Guide,2008,10(6):904-905.
Authors:Liu Jun Xiang Liang-bi Cheng Yu  
Institution:Liu Jun Xiang Liang-bi Cheng Yu,et al.(Department of Orthopaedics,The General Hospital of Shenyang Military Area Comm,,Shenyang 110015,China)
Abstract:Objective:To investigate the effects of three-dimensional rectification apparatus on inflammatory cells and asrway remodel- ing of guinea pigs.Method:Guinea pigs were divided into the treated group,the bronchial asthma group and the control,10 pigs per group.The model was made and treated with three-dimensional rectification apparatus and was killed after two weeks.The bronchial tissues were taken out,dyed through FIE and observed through the Optical Microscope.Results:It has no apparent changes for inflamm...
Keywords:bronchial asthma  airway remodeling  three-dimensional rectification apparatus  
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