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糖复康胶囊治疗糖尿病肾病的主要药效学研究
引用本文:岳 南,只德广,赵益桂,苏 雅. 糖复康胶囊治疗糖尿病肾病的主要药效学研究[J]. 医学教育探索, 2009, 24(1): 43-48
作者姓名:岳 南  只德广  赵益桂  苏 雅
作者单位:天津药物研究院新药评价中心,天津 300193
摘    要:目的 观察糖复康胶囊对糖尿病肾病的治疗作用。方法 采用糖尿病肾病、高血糖、血瘀等实验模型,观察、测定相应的实验指标。结果 糖复康胶囊对糖尿病肾病有明显的防治作用;降低高血糖动物的血糖;抑制高分子右旋糖酐所致大鼠全血黏度的升高;抑制动脉血栓形成。结论 糖复康胶囊对糖尿病肾病有明显的防治作用。

关 键 词:糖复康胶囊;糖尿病肾病;高血糖;高黏滞血症;血栓

Pharmacodynamics of therapeutic effects of Tangfukang Capsula on diabetic nephropathies
YUE Nan,ZHI De-guang,ZHAO Yi-gui,SU Ya. Pharmacodynamics of therapeutic effects of Tangfukang Capsula on diabetic nephropathies[J]. Researches in Medical Education, 2009, 24(1): 43-48
Authors:YUE Nan  ZHI De-guang  ZHAO Yi-gui  SU Ya
Affiliation:Center for Drug Evaluation and Research in Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China
Abstract:Objective To study the therapeutic effects of Tangfukang Capsula on diabetic nephropathies (DN). Methods The diabetic nephropathies, hyperglycosemia, and blood stasis models were used to observe the appropriate test targets. Results The Tangfukang Capsula showed the preventive and therapeutic effect on DN, it could reduce the blood sugar level of the animals with hyperglycosemia, suppress the higher viscosity of whole blood by polymer dextran-induced and artery thrombosis in rat5. Conclusion Tangfukang Capsula has bovious preventive and therapeutic effects in animals with DN.
Keywords:Tangfukang Capsula   diabetic nephropathies   cyperglycosemia   blood hypervicosity   thrombosis
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