泌尿系患者真菌感染的病原学和耐药性研究

目的研究住院患者泌尿系真菌感染病原学特点及其耐药性,为泌尿系真菌感染的防治提供参考数据。方法通过对尿液标本细菌学检验和分离鉴定以及药敏试验,对该医院临床科室泌尿系感染患者尿液标本进行了检测与分析。结果该医院2010年度从28 804例住院患者的尿液标本中检出真菌492株,真菌检出率为1.71%;其中从4 042例中段尿中检出真菌484株,检出率为11.97%。尿液标本中真菌检出率最高的患者来自重症医学科,其次是泌尿科和神经外科。尿液标本检出的真菌中,以热带假丝酵母菌居首位,构成比为74.4%;其次为白色假丝酵母菌和光滑假丝酵母菌。居前3位的真菌中,以光滑假丝酵母菌耐药性最强。结论泌尿系感染患者采集中段尿真菌检出率最高,以热带假丝酵母菌为主,主要患者分布在重症医学科,以光滑假丝酵母菌耐药性最强。

STUDY ON AETIOLOGY AND DRUG-RESISTANCE OF FUNGAL INFECTION IN URINARY TRACT PATIENTS

Objective To research the pathogenic character and drug-resistance of urinary tract infection in-patients,and to provide reference data for prevention and control.Methods Bacteriological examination,isolation,identification,and drug sensitive test were used to detect and analyses the urine specimens of the urinary tract infection patients.Result In 2010,the fungal detection rate of urine routine examination in 28 804 cases of hospitalized patients was 1.71%(492 cases).The fungal culture rate of 4 042 cases of midstream urine detection was 11.97%(484 cases).The highest fungi detection rate was in ICU,next was in urology department and neurosurgery.Candida tropicalis was the most,the constituent ratio of Candida tropicalis was 74.4%,next were White candida mycoderma bacteria and Smooth candida yeast.The drug-resistance of Smooth candida yeast was the strongest.Conclusion The detection rate of midstream urine was highest,most was Candida tropicalis and major distributed in ICU,the drug-resistance of Smooth candida yeast was the strongest.