| 不同产地五味子药材的质量特征比较研究 |
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| 引用本文： | 周永峰,王伽伯,张定堃,谭鹏,张海珠,李宝才,肖小河. 不同产地五味子药材的质量特征比较研究[J]. 中国中药杂志, 2015, 40(16): 3152-3157 |
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| 作者姓名： | 周永峰 王伽伯 张定堃 谭鹏 张海珠 李宝才 肖小河 |
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| 作者单位： | 昆明理工大学 生命科学与技术学院, 云南 昆明 650093;解放军302医院 全军中医药研究所, 北京 100039,解放军302医院 全军中医药研究所, 北京 100039,解放军302医院 全军中医药研究所, 北京 100039;成都中医药大学 药学院, 四川 成都 611137,解放军302医院 全军中医药研究所, 北京 100039;成都中医药大学 药学院, 四川 成都 611137,解放军302医院 全军中医药研究所, 北京 100039;成都中医药大学 药学院, 四川 成都 611137,昆明理工大学 生命科学与技术学院, 云南 昆明 650093,解放军302医院 全军中医药研究所, 北京 100039 |
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| 基金项目： | 国家自然科学基金项目(81274026) |
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| 摘 要： | 该文采用HPLC同时测定五味子药材中五味子醇甲、五味子醇乙、五味子酯甲、五味子甲素、五味子乙素、五味子丙素等6种化学成分的含量,同时收集不同批次五味子的百粒重,颜色,五味子果肉含量以及经纬度等参数,分别使用SIMCA-P软件和SPSS软件对24批五味子药材进行PLS-DA分析以及相关参数的相关性分析。实验发现根据这13个参数指标能够将3个不同产地的五味子有效区分,五味子的化学成分含量随着经度、纬度的增加呈现出先增加后降低的趋势。该结论为五味子道地性的研究以及传统经验鉴别提供一定的理论依据。
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| 关 键 词： | 不同产地 五味子 质量特征 PLS-DA分析 相关性分析 |
| 收稿时间： | 2015-03-26 |
Quality characteristic comparison of Schisandrae Chinensis Fructus from different place |
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| ZHOU Yong-feng,WANG Jia-bo,ZHANG Ding-kun,TAN Peng,ZHANG Hai-zhu,LI Bao-cai and XIAO Xiao-he. Quality characteristic comparison of Schisandrae Chinensis Fructus from different place[J]. China Journal of Chinese Materia Medica, 2015, 40(16): 3152-3157 |
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| Authors: | ZHOU Yong-feng WANG Jia-bo ZHANG Ding-kun TAN Peng ZHANG Hai-zhu LI Bao-cai XIAO Xiao-he |
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| Affiliation: | Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650093, China;China Military institute of Chinese Medicine, 302 Military Hospital of China, Beijing 100039, China,China Military institute of Chinese Medicine, 302 Military Hospital of China, Beijing 100039, China,China Military institute of Chinese Medicine, 302 Military Hospital of China, Beijing 100039, China;College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China,China Military institute of Chinese Medicine, 302 Military Hospital of China, Beijing 100039, China;College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China,China Military institute of Chinese Medicine, 302 Military Hospital of China, Beijing 100039, China;College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China,Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650093, China and China Military institute of Chinese Medicine, 302 Military Hospital of China, Beijing 100039, China |
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| Abstract: | The contents of schisandrol A, schisandrol B, schisantherin A, schisandrin A, schisandrin B, schisandrin C in Schisandrae Chinensis Fructus (SCF) were determined simultaneously by HPLC. Collect 100-seed weight, color, pulp content, longitude and latitude of SCF of different batches were collected. SIMCA-P and SPSS were applied to make PLS-DA analysis of 24 batches of SCF and correlation analysis of relevant parameters. According to the 13 parameters, SCF from three different places of origin could be distinguished effectively. It was found that the content of chemical component of SCF increased with latitude and longitude first, and then decrease. The results provide some theoretical basis for study of SCF genuineness and traditional method of identifying just from experience. |
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| Keywords: | different places Schisandrae Chinensis Fructus quality characteristics PLS-DA analysis correlation analysis |
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