宫颈微小偏离型腺癌临床病理观察

且的探讨宫颈微小偏离型腺癌（MDA）的临床病理特征，免疫组化及鉴别诊断。方法对1例MDA进行组织形态学、免疫组化观察和文献复习。结果MDA临床症状以宫颈水样溢液为主，伴／不伴接触性出血，体征多数为宫颈肥大和／或宫颈糜烂。手术前活检难于确诊，术后根据腺体浸润宫颈深度和免疫标记CEA、CA125、ER、PR、Ki-67等确诊。结论宫颈MDA的早期确诊率极低，应警惕宫颈水样溢液和／或宫颈肥大者，应争取宫颈深部（〉7mm）活检，必要时施行高频电刀宫颈锥形切除术。大多数病例需要术后确诊。

The clinical and pathological observation of minimal deviation adenocarcinoma

Objective To explore the histopathologic and immunohemical characteristics of minimal deviation adenocarcinoma （MDA） and its differential diagnosis. Methods We observed the histopathologic and immunohistochemical results in one case of mixed MDA and the related literature was reviewed, Results The MDA main symptoms included the watery discharge of cervix, with or without the irregular hemorrhage of uterus. Most patients had the singns of cervical hypertrophy and/or erosion. Before the surgery, the biopsy difficulty with diagnoses, after the technique, infiltrates the cervix of the uterus depth and the immunity according to the gland marks diagnoses and so on CEA, CA125, ER, PR, Ki -67. Conclusion The early diagnosis rate of the cervical MDA is very low, we must pay more attention. For patients with watery dis- charge and/or hypertrophy of cervix, the deep （ 〉7 mm） biopsies should be performed. Electric knife conization should be performed of it necessary.