鞍区颗粒细胞瘤的诊治分析:附3例报道并文献复习

目的 探讨鞍区颗粒细胞瘤(GCT)的临床特点、诊断及治疗方法.方法 回顾性分析经术后病理检查证实的3例鞍区GCT的临床资料,并结合文献进行分析.结果 行扩大翼点入路手术2例,其中肿瘤全切除1例,次全切除1例;行经鼻蝶入路神经内镜手术全切除肿瘤1例.术后症状均改善,术后出现一过性尿崩症1例,垂体功能减退1例.3例术后均未...

Diagnosis and treatment of patients with sellar granulosa cell tumor: report of 3 cases and literature review

Objective To explore the clinical features, diagnosis and treatment of the patients with sellar granulosa cell tumor (GCT). Methods The clinical data of 3 patients with sellar GCT who were definitely diagnosed by postoperative pathological examinationwere retrospectively analyzed. The related literatures were reviewed. Results Microsurgery through extended pterional approach wasperformed on 2 patients, of whom 1 patient received total tumor resection and 1 subtotal. Neuroendoscopic surgery through nasalsphenoid approach was performed on 1 patient who received total tumor resection. Preoperative symptoms were improved after theoperation. Transient diabetes insipidus occurred in 1 patients, and hypopituitarism in 1 after the surgery. All the patients did not undergoradiotherapy and chemotherapy. The follow-up (range, 18~60 months) showed no tumor recurrence or progression. Conclusions Sellar GCT is extremely rare. For the lesions in the sellar and/or suprasellar region, the GCT should be considered when their CT images showslightlyhigherdensitiesthan cerebraltissues,and theriMRIimagesshowiso-intensityon T1-and T2-weighted images and uniform ornon-uniform enhancement. For treatment of sellar GCT, neuroendoscopic transnasal sphenoid surgery is preferentially recommended,which can safely and minimally invasively remove the tumors.