手术对颞叶癫痫病人认知功能的影响

目的 探讨手术对颞叶癫痫病人认知功能的影响.方法 回顾性分析2017年1月至2020年1月手术治疗的60例颞叶癫痫的临床资料.38例采用前颞叶切除术(ATL)治疗,22例采用选择性海马杏仁核切除术(SAH)治疗.术后6个月,采用Engle分级评估预后.术前、术后6个月由专业人员采用面对面形式完成认知功能评估,采用韦氏智...

Effect of surgery on cognitive function of patients with temporal lobe epilepsy

Objective To evaluate the effect of surgery on the cognitive function of the patients with temporal lobe epilepsy (TLE). Methods A retrospective analysis was performed on the clinical data of 60 patients with TLE who underwent surgical treatment from January 2017 to January 2020. Of 60 TLE patients, 38 patients received anterior temporal lobectomy (ATL) and 22 patients received selective amygdalo-hippocampectomy (SAH). The Engle class was used to assess the outcomes 6 months after the operation. Memory quotient (MQ) and intelligence quotient (IQ) were measured by adult Wechsler Memory Scale and adult Wechsler Intelligence Scale before surgery and 6 months after surgery, respectively. Results Six months after the operation, Engle class Ⅰ was achieved in 35 patients, class Ⅱ in 20 and class Ⅳ in 5. Both MQ and IQ were significantly higher after the surgery than those before the surgery in both groups (P<0.05). Moreover, the MQ of patients in SAH group was significantly higher than that of patients in ATL group (P<0.05). Conclusions Surgical treatment improves IQ and MQ of the TLE patients. The effect of SAH on MQ of TLE patients was better than that of ATL.