脊柱外科术后脑脊液漏并颅内感染的诊治分析

目的 探讨脊柱外科术后脑脊液漏并颅内感染的治疗方案及临床疗效.方法 回顾性分析2014年1月至2020年1月收治的11例脊柱外科手术后发生脑脊液漏并颅内感染的临床资料.5例单纯抗感染治疗,1例保持引流并抗感染治疗,5例抗感染联合腰大池引流治疗.结果 11例感染均有效控制;术后至出现发热时间5～11 d,平均(7.46±...

Treatment of cerebrospinal fluid leakage associated with intracranial infection after spinal surgery

Objective To investige the management and outcome of cerebrospinal fluid leakage (CSFL) associated withintracranial infection after the spinal surgery. Methods A retrospective analysis was performed on the clinical data of 11 patients withCSFL associated with intracranial infection after the spinal surgery. According to the severity of CSFL, 5 patients were treated withsimple anti-infection,1 was keeping the subcutaneous drainage tube and treated with anti-infection, 5 were treated with anti-infectioncombined with lumbar cistern drainage. Results The infections of 11 patients were effectively controlled after the treatment. The timefrom operation to infection ranged from 5 days to 11 days, with an average of (7.46±1.75) days. The anti-infection period of 11 patientsranged from 14 days to 23 days, with an average of (19.55±2.73) days. The time for leukocyte level in CSF to return to normal rangedfrom 10 dyas to 19 days, with an average of (15.27±3.58) days. The time for quantification of CSF glucose to return to normal rangedfrom 8 days to 16 days, with an average of (12.91±2.74) days. Conclusions For patients with CSFL associated with intracranial infectionafter the spinal surgery, the treatment methods should be selected according to the status of CSFL. Early diagnosis and control ofinfection are the key to successful treatment. Continuous lumbar cistern drainage combined with anti-infection is helpful in thetreatment of patients with severe CSFL associated with intracranial infection.