| 黄芩苷在呼吸道黏膜慢性炎症性疾病中的抗炎作用及机制研究进展 |
| |
| 引用本文： | 黄芩苷在呼吸道黏膜慢性炎症性疾病中的抗炎作用及机制研究进展.黄芩苷在呼吸道黏膜慢性炎症性疾病中的抗炎作用及机制研究进展[J].首都医学院学报,2022,43(6):919-923. |
| |
| 作者姓名： | 黄芩苷在呼吸道黏膜慢性炎症性疾病中的抗炎作用及机制研究进展 |
| |
| 作者单位： | 1.首都医科大学附属北京同仁医院耳鼻咽喉头颈外科,北京100730; 2.北京市耳鼻咽喉科研究所,北京100005; 3.首都医科大学附属北京佑安医院耳鼻咽喉科,北京100069; 4.首都医科大学附属北京同仁医院变态反应科,北京100730; 5.中国医学科学院慢性鼻病诊疗策略研究创新单元,北京 100005 |
| |
| 基金项目： | 教育部长江学者创新团队(IRT13082),中国医学科学院医学与健康科技创新工程项目(2019-I2M-5-022),北京市科技计划首都健康保障培育研究项目(Z181100001618002)。 |
| |
| 摘 要： | 黄芩苷是源于中药黄芩根部的黄酮类化合物,是黄芩的主要活性成分,其药理作用广泛,具有良好的抗炎、抗癌、抗病毒和抗氧化等作用。以慢性鼻窦炎、过敏性鼻炎和哮喘为主的呼吸道黏膜慢性炎症性疾病是影响人类日常生活的严重慢性疾病之一,其发病机制复杂,目前对于此类疾病的治疗易产生不良反应且有一定的局限性。中药成分黄芩苷因其抗炎效果好,不良反应小而具有开发为治疗呼吸道黏膜慢性炎症性疾病的药物潜能。本文对黄芩苷在呼吸道黏膜慢性炎症性疾病中的抗炎作用及机制研究进展进行总结和归纳,为其在相关疾病的临床应用提供理论依据。
|
| 关 键 词： | 黄芩苷 呼吸道黏膜慢性炎症 抗炎作用 研究进展 |
| 收稿时间： | 2022-09-06 |
Research advances in the anti-inflammatory effects and mechanisms of baicalin in chronic inflammatory diseases of respiratory mucosa |
| |
| Yang Jingxing,Cai Chao,Zhao Yan,Wang Xiangdong,Zhang Luo.Research advances in the anti-inflammatory effects and mechanisms of baicalin in chronic inflammatory diseases of respiratory mucosa[J].Journal of Capital University of Medical Sciences,2022,43(6):919-923. |
| |
| Authors: | Yang Jingxing Cai Chao Zhao Yan Wang Xiangdong Zhang Luo |
| |
| Abstract: | Baicalin is a kind of flavonoid component derived from the root of Scutellaria baicalensis, the main active ingredient of the plant. It has a wide range of pharmacological effects such as anti-inflammatory, anti-cancer, antiviral and antioxidant effects.Chronic inflammatory diseases of the respiratory mucosa, mainly chronic rhinosinusitis, allergic rhinitis and asthma, are among the serious chronic diseases affecting human daily life. The pathogenesis is complex and the current therapeutic methods have certain limitations and adverse effects.The traditional Chinese medicine baicalin has the potential to be developed as a drug for the treatment of chronic inflammatory diseases of the respiratory mucosa because of its good anti-inflammatory effect and low toxic side effects.In this review, we summarize the anti-inflammatory mechanism of baicalin in chronic inflammatory diseases of the respiratory mucosa and provide theoretical basis for its clinical application in related diseases. |
| |
| Keywords: | baicalin chronic inflammation of respiratory mucosa anti-inflammatory effect research advances |
|
| 点击此处可从《首都医学院学报》浏览原始摘要信息 |
| 点击此处可从《首都医学院学报》下载免费的PDF全文 |
