SII和PNI与动脉瘤性蛛网膜下腔出血预后的关系

目的 探讨入院时全身免疫炎症指数(SII)和预后营养指数（PNI）水平与动脉瘤性蛛网膜下腔出血（a SAH）病人预后的关系。方法 回顾性分析2019年9月至2021年2月收治的165例aSAH的临床资料。出院3个月，采用GOS评分评估预后，其中4～5分为预后良好，1～3分为预后不良。结果 165例中，预后良好103例，预后不良62例。多因素logistic回归分析示，入院时SII≥2825.59×109/L是aSAH病人预后不良的独立危险因素（OR=4.387;95%CI 1.313～14.655;P=0.016）,PNI≥50.73是预后良好的保护因素（OR=0.240;95%CI 0.076～0.757;P=0.015）。结论 SII、PNI与aSAH的预后有关，入院时SII、PNI水平有助于早期预测aSAH的预后。

Relationship between SNI and PNI with prognosis of patients with aneurysmal subarachnoid hemorrhage

Objective To investigate the relationship of immune-inflammation index (SII) and prognostic nutritional index (PNI)levels on admission with prognosis of patients with aneurysmal subarachnoid hemorrhage (aSAH). Methods The clinical data of 165 aSAH patients who were admitted to our hospital between September 2019 and February 2021 were retrospectively analyzed. The GOS score was used to assess the prognosis of the patients 3 months after discharge, with GOS score of 4~5 as good prognosis and score of 1~3 as poor prognosis. Results Of 165 aSAH patients, 103 had a good prognosis and 62 had a poor prognosis. Multivariate logistic regression analysis showed that SII ≥2825.59×109/L was a independent risk factor for the poor prognosis of aSAH patients (OR=4.387; 95% CI 1.313~14.655; P=0.016), and PNI≥50.73 was a protective factor for the good prognosis of aSAH patients (OR=0.240; 95% CI 0.076~0.757; P=0.015). Conclusions SII and PNI are related to the prognosis of patients with aSAH. The levels of SII and PNI on admission are helpful to early evaluate the prognosis of aSAH patients.