Abstract: | Viruses and bacteria cause diseases of vast economic importance. Sialidase inhibitors offer an opportunity to prevent or ameliorate these diseases. They have been investigated ostensibly as antiviral agents particularly against influenza viruses. The patent literature covering sialidase inhibitor compounds, their design and synthesis is reviewed from 1995 to mid-1998 with reference to the primary scientific literature. Patents are discussed by company or institution. The importance of different compound types is indicated. |