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Medications in pregnancy and breastfeeding
Affiliation:1. Sandwell & West Birmingham Hospitals NHS Trust, Birmingham, UK;2. Rheumatology Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK;1. Department of Pediatrics, Texas Tech University Health Sciences Center, 1400 Wallace Boulevard, Amarillo, TX 79106, USA;2. Department of Obstetrics and Gynecology, Texas Tech University Health Sciences Center, 1400 Coulter Street, Amarillo, TX 79106, USA;1. Discipline of Pharmacy, University of Canberra, University Drive, Bruce, ACT, 2617, Australia;2. Faculty of Health, University of Canberra, University Drive, Bruce, ACT, 2617, Australia;3. Discipline of Pharmacy, Queensland University of Technology, 2 George St, Brisbane, QLD, 4000, Australia;1. Rheumatology and Immunology Unit, Department of Clinical and Experimental Sciences, University of Brescia and ASST Spedali Civili of Brescia, Piazzale Spedali Civili 1, 25123, Brescia, Italy;2. Child Neurology and Psychiatry Unit, Clinical and Experimental Sciences Department, University of Brescia and ASST Spedali Civili Brescia, Piazzale Spedali Civili 1, 25123, Brescia, Italy;1. Departments of Internal Medicine and OB/GYN, University of Michigan Medical School, NCRC B14-G236, 2800 Plymouth Rd, Ann Arbor, MI 48109-2800, USA;2. Department of Internal Medicine, University of Michigan Medical School, NCRC B300-304M, Ann Arbor, MI 48109-2800, USA;3. Departments of Internal Medicine, OB/GYN, and Environmental Health Sciences, University of Michigan Schools of Medicine and Public Health, NCRC B14-G236, 2800 Plymouth Rd, Ann Arbor, MI 48109-2800, USA
Abstract:Advances in therapeutics, including a wider use of biologics and targeted synthetic disease-modifying anti-rheumatic drugs (DMARDs) have substantially improved the management of rheumatic diseases, resulting in more women with severe disease considering pregnancy. Every clinical rheumatologist has encountered a woman who wishes to have a pregnancy – or who presents already pregnant – and who values the importance of reliable information on rheumatic diseases and safety of medications in pregnancy. This chapter summarises current evidence and knowledge on the use of ‘Medications in pregnancy and breastfeeding in women with rheumatic diseases’ and considers paternal medication use at the time of conception.
Keywords:Pregnancy  Breastfeeding  DMARDs  Corticosteroids  Biologics  Rheumatic disease
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