Alcohol Biomarkers: Clinical Significance and Biochemical Basis |
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| Authors: | Raj Lakshman Mikihiro Tsutsumi P Ghosh S Takase H Anni O Nikolaeva Y Israel R F Anton O M Lesch A Helender G Eriksson J-O Jeppson P Marmillot M N Rao |
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| Institution: | Lipid Research Laboratory, DVA Medical Center and Department of Medicine (RL, PG, PM, MNR), The George Washington University, Washington, DC;the Division of Gastroenterology (MT, ST), Department of Internal Medicine, Kanazawa Medical University, Japan;the Department of Pathology-Anatomy and Cell Biology (HA, ON, YI), Alcohol Research Center, Thomas Jefferson University, Philadelphia, Pennsylvania;the Department of Psychiatry and Behavioral Sciences (RFA), Center for Drug and Alcohol Programs, Medical University of South Carolina, Charleston, South Carolina;the Department of Psychiatry and Anton Proksch Institute (OML), University of Vienna, Austria;and the Departments of Clinical Neuroscience and Clinical Chemistry (AH, GE, J-OJ), Karolinska Institute and Hospital, Stockholm, Sweden. |
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| Abstract: | This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Raj Lakshman and Mikihiro Tsutsumi. The presentations were (1) Sialic acid index of apolipoprotein J: A new marker for chronic alcohol consumption, by P. Ghosh and M. R. Lakshman; (2) Microheterogeneity of serum glycoproteins in alcoholics, by M. Tsutsumi and S. Takase; (3) Probing protein-ethanol adducts with combinatorial peptide libraries displayed by filamentous phage, by H. Anni, O. Nikolaeva, and Y. Israel Y; (4) Carbohydrate-deficient transferrin as a marker for heavy alcohol use: What have we learned; Where do we go from here, by R. F. Anton; (5) Sensitivity and specificity of carbohydrate-deficient transferrin in drinking experiments and different patient groups, by O. M. Lesch; (6), Transferrin variants interfere with the measurement of carbohydrate-deficient transferrin, by A. Helender, G. Eriksson, and J-O. Jeppson; and (7) Chronic ethanol on protein trafficking in liver, by P. Marmillot, M. N. Rao, and M. R. Lakshman. |
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| Keywords: | Sialic Acid Glycoproteins Peptide Carbohydrate-Deficient Transferrin Liver |
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