灰树花化学成分和药理作用的研究进展

灰树花Grifola frondosa为担子菌亚门、树花菌属真菌，是一种药、食用菌。其化学成分有多糖、蛋白质等，药理作用涵盖免疫调节、抗肿瘤、抗糖尿病、抗高脂血、抗病毒等方面。近年来，对灰树花化学成分与药理活性的研究受到了广泛的关注，一些临床试验也相继开展。现对灰树花的化学成分与药理活性研究概况进行综述，以期为灰树花的全面开发和深入研究提供参考。

Research advances on chemical constituents and pharmacological effect of Grifola frondosa

Grifola frondosa, a species of Basidiomycotina, is an edible and medicinal fungus. Its chemical constituents include polysaccharides and proteins as well. The pharmacological effect of G. frondosa covers immunomodulatory, antidiabetic, anti-hyperlipidemia, antivirus, and antitumor effects, etc. The chemical constituents of G. frondosa and the researches on pharmacological effect of G. frondosa have been concerned widely. And some clinical trials have been carried out in recent years. Recent studies on chemical constituents and pharmacological effect of G. frondosa were reviewed in this paper. Moreover, references for the full development and in-depth study of G. frondosa have been offered.