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Retroperitoneal Fibrosis as a Result of Signet Ring Cell Gastric Cancer: a Case-Based Review |
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| Authors: | Ashraf Karbasi Reza Karbasi-Afshar Javad Ahmadi Amin Saburi |
| Affiliation: | 1. Baqiyatallah Research Center of Gastroenterology and Liver Disease, Baqiyatallah University of Medical Sciences, Tehran, Islamic Republic of Iran 2. Department of Cardiology, Baqiyatallah University of Medical Sciences, Tehran, Islamic Republic of Iran 3. Health Research Center, Baqiyatallah University of Medical Sciences, Tehran, Islamic Republic of Iran 4. Nephrology Department, Baqiyatallah University Hospital, Tehran, Islamic Republic of Iran 5. Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Vanak Sq, Mollasadra St, Tehran, Islamic Republic of Iran |
| Abstract: | BackgroundRetroperitoneal fibrosis is a rare and obvious condition in the abdominopelvic cavity. Signet ring cell carcinoma of the stomach with gross appearance of linitis plastica is another rare association.Case presentationWe present a rare case of a 49-year-old woman presenting with persistent nausea and vomiting for 20 days. Three months ago, she was admitted with severe flank pain and was referred to the urology service. She was placed with stents for strictures in both ureters. She underwent endoscopy for heartburn, melena, dyspepsia, and weight loss (7 kg/5 month), which revealed congestion of the mucosa of the fundus and body with fine linear erosion and decreased distensibility of the stomach suggesting linitis plastica. A biopsy indicated full-thickness infiltration by signet ring cell gastric cancer. A CT scan showed evidence of retroperitoneal fibrosis with large lymph nodes around the aorta.ConclusionThis paper shows that the gastric linitis plastica can present with many deceptive clinical presentations, raising the risk of postponed diagnosis. |
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