| 哒嗪和哒嗪酮碳核苷类似物的合成 |
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| 引用本文： | 孙德群,朱京,马灵台,张礼和. 哒嗪和哒嗪酮碳核苷类似物的合成[J]. 华西药学杂志, 1999, 14(3): 149-151 |
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| 作者姓名： | 孙德群 朱京 马灵台 张礼和 |
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| 作者单位： | 1. 中国科学院成都有机所,成都,610041
2. 北京医科大学药学院,北京,100083 |
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| 摘 要： | 用杂环金属盐法，通过呋喃碳核苷中间体，合成了哒嗪、哒嗪酮等碳核苷，并讨论了反应机理提高了呋喃汞盐合成碳核苷的收率及立体选择性。
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| 关 键 词： | 哒嗪 哒嗪酮 碳核苷 |
SYNTHESIS OF PYRIDAZINE AND PYRIDAZINONE C-NUCLEOSIDE ANALOGUES |
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| Sun Dequn,Zhu Jing,Ma Lingtai,Zhang Lihe. SYNTHESIS OF PYRIDAZINE AND PYRIDAZINONE C-NUCLEOSIDE ANALOGUES[J]. West China Journal of Pharmaceutical Sciences, 1999, 14(3): 149-151 |
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| Authors: | Sun Dequn Zhu Jing Ma Lingtai Zhang Lihe |
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| Affiliation: | Sun Dequn;( |
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| Abstract: | New Cnucleoside analogues were synthesized via the key intermediate 2(2',3',4'triObenzoylDxylopyranosyl)furan.The stability of the and isomer was described. The conversion of the furan ring into pyridazine ring was performed by ClassonKaas method to give 3(Dxylopyranosyl)pyridazine and 3(Dxylopyranosyl4,5dihydro6(1H))pyridazinone. |
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| Keywords: | PyridazinePyridazinoneCnucleoside |
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