| 通鼻胶囊对急性炎症的影响 |
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| 引用本文： | 于海玲,孙莲平,黄明爱,洪淳赞.通鼻胶囊对急性炎症的影响[J].延边医学院学报,2004,27(2):112-115. |
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| 作者姓名： | 于海玲 孙莲平 黄明爱 洪淳赞 |
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| 作者单位： | [1]延边大学医学院药理学教研室，吉林延吉133000 [2]延边大学医学院机能学实验室，吉林延吉133000 [3]延边大学医学院流行病学教研室，吉林延吉133000 |
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| 摘 要： | 目的 ]研究通鼻胶囊对急性炎症的药理作用 ,同时观察其急性毒性 .方法 ]建立多种实验性急性炎症的动物模型 .结果 ]通鼻胶囊呈剂量依赖性地抑制二甲苯和巴豆油所致的小鼠耳壳肿胀 ;对角叉菜胶诱导的大鼠足跖肿胀也有明显的抑制作用 ,作用持续时间达 6h以上 ;小鼠对通鼻胶囊的最大耐受量达成人用量的 16 2倍 .结论 ]通鼻胶囊对急性炎症有一定的抑制作用 ,且毒性小 .
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| 关 键 词： | 炎症 急症 药物疗法 小鼠 |
| 文章编号： | 1000-1824(2004)02-0112-03 |
| 修稿时间： | 2003年10月9日 |
Effects of the Tongbi capsule for acute inflammation |
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| YU Hai-ling,SUN Lian-ping,HUANG Ming-ai,HONG Chun-zan.Effects of the Tongbi capsule for acute inflammation[J].Journal of Medical Science Yanbian University,2004,27(2):112-115. |
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| Authors: | YU Hai-ling SUN Lian-ping HUANG Ming-ai HONG Chun-zan |
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| Institution: | YU Hai-ling1,SUN Lian-ping2,HUANG Ming-ai3,HONG Chun-zan 1 |
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| Abstract: | OBJECTIVE?To study the effects of the Ton gb i (Tb) capsule for acute inflammation and acute toxicity.?METHODS?The therapeutic effects of the Tb capsule for acute inflammation were obser ved by establishing several models in rats and mice.?RESULTS?The Tb capsule inhibited, in a dose dependent manner, the ear swelling of mi ce induced by xylene and croton oil and the swelling of hind paws in rats induce d by carrageenin, and the effective time lasted for 6 hours, and the maximum tolerance dose of the Tb capsule was more than 162 times than that of human.?CONCLUSION?The Tb capsule has inhibitory effects for acute inflammation and its toxis ity is very little. |
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| Keywords: | inflammation emergencies drug therapy mice |
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