颈部大动脉粥样硬化与短暂性脑缺血发作的相关研究

目的　评价颈部大动脉粥样硬化与短暂性脑缺血发作 (TIA)的相关性。方法　对 16 8例TIA患者进行颈部大动脉彩色多普勒检测 ,同期来院健康体检者 6 0例为对照组。结果　TIA患者颈动脉内膜中层厚度 (IMT)和斑块的发生率较对照组明显增加 ,两组比较差异有显著性意义 (P <0 .0 1)。椎 基底动脉系统TIA患者锁骨下动脉起始处的斑块发生率明显多于颈内动脉系统TIA患者 ,差异有显著性意义 (P <0 .0 1)。TIA患者颈内动脉的IMT值与血浆总胆固醇、甘油三酯、纤维蛋白原的含量成正相关 (P <0 .0 1)。结论　彩色多普勒超声可作为颈部大动脉粥样硬化检测的可靠方法。颈部大动脉粥样硬化的形成与TIA的发病密切相关

Correlation between neck artery atherosclerosis and transient ischemic attack

Objective To investigate the relationship between neck artery atherosclerosis and transient ischemic attack(TIA).Methods Color Doppler ultrasonography was used in 168 patients with TIA.Results Intima media thickness(IMT) of carotid arteries was higher in patients with TIA than in control group.The rates of arterioclerotic plaques of carotid arteries were increased significantly in patients with TIA than in controls.The arterioclerotic plaques were mainly found at the beginning of subclavian artery in vertebrobasilar TIA than in carotid TIA.A significant positive correlation between the IMT of internal carotid artery and the concentration of blood total cholesterol,triglyceride,fibrinogen,respectively.Conclusions Color Doppler ultrasonography is a reliable technique to evaluate the arterioclerotic plaques of neck arteries.There is a significant correlation between neck artery atherosclerosis and TIA.